Nazivin drops for children: instruction manual

Nazivin is a known pharmaceutical agent widely used for medical purposes in cases of ENT diseases and colds.

The main active ingredient of the drug is oxymetazoline. This substance stimulates the work of α2-adrenoreceptors, as a result of which a greater the number of hormones norepinephrine and adrenaline, which both reduce puffiness, narrowing blood vessels, reducing blood volume in them. Due to this effect, nasal breathing is facilitated, air penetration into the sinuses is provided, the amount of mucus released is reduced.

For this purpose, the medication is used not only for adults, the widespread and Nazivin children's, which has various forms of release, such as Nazivin Baby, Nazivin Sensitiv, etc.

Clinical and pharmacological group

Vasoconstrictive drug for topical application in ENT practice.

Conditions of leave from pharmacies

Released without a doctor's prescription.

Price list

How much is Nazivin? The average price in pharmacies is at the level of140 rubles.

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Form of issue and composition

The active substance of the drug is oxymetazoline.

Children's Nizivin is released in solution, 25% and, 1%. The basis of the solution is aqueous. It contains additional components: disodium edetate, benzalkonium chloride 50%, sodium hydrogen phosphate, sodium hydroxide 1 ml solution. Produced in dark glass vials of 5 ml or 10 ml with a pipette in the lid.

Applying to children up to a year, drops are diluted with special water used for injections in the proportion: or distilled in the same proportion. Used for instillation into the spout.

Pharmacological effect

When Nazivin gets on the inflamed mucous membrane of the nose, its swelling and the volume of mucus released decreases. This is due to the effect of the drug on adrenaline receptors, which are in the blood vessels (in the muscle fibers). The receptors are reduced, and the permeability of the vessels decreases due to their constriction.

The use of Nazivin improves nasal breathing, eliminates the swelling of mucous membranes. And also the drug reduces the risk of complications in the paranasal sinuses and in the middle ear (sinusitis, sinusitis and otitis). After getting the drug into the blood due to absorption in the mucous membranes, the vessels (arteries) contract in the organs and tissues, and the heart rate also increases. This increases blood pressure, and changes the heart rate.

When applying Nazivin to mucous membranes in recommended doses, it does not enter the circulatory system and does not cause systemic effects on the body. Nazivin does not irritate the nasal mucosa and does not cause blood vessel overflow (hyperemia).

The maximum exposure to the drug is reached after 15 minutes after use. The action lasts for 8 hours.

Indications for use

What helps? Nazivin is used for:

• ARI, if there is a runny nose;
• sinusitis, eustachyte, middle otitis and inflammation of the paranasal sinuses to facilitate the outflow of mucus;
• preparation of nasal passages to diagnostic procedures;
• allergic and vasomotor rhinitis.

Contraindications

When applying the product it is important to follow the rules given in the instructions, then the substance can be digested even to babies under 1 year. However, the drug has a number of contraindications. In some cases, its use will have to be abandoned:

• Children under 6 years of age (drops and spray nasal 0.05%);
• atrophic rhinitis;
• angle-closure glaucoma;
• hypersensitivity to the components of the drug.

It is recommended to adhere to recommended concentrations of the drug, intended for different age categories.

With caution should be appointed with the simultaneous use of MAO inhibitors and other drugs that promote blood pressure, and also in the period up to 10 days after the cancellation of these medicines; with increased intraocular pressure; during pregnancy and during lactation; with severe forms of cardiovascular diseases (arterial hypertension, angina pectoris); with thyrotoxicosis and sugar diabetes.

Use in pregnancy and lactation

When used during pregnancy or breastfeeding, the recommended dosage should not be exceeded. The drug should only be used after a thorough assessment of the risk-benefit relationship for the mother and fetus.

Dosage and route of administration

The instructions for use indicate that Nazivin drops are intended for intranasal use.

Children under the age of 1 year are prescribed drops of 0.01%.

1. Newborns (children under 4 weeks) are administered 1 drop in each nostril 2-3 times / day.
2. Children aged 1 month to 1 year are prescribed 1-2 drops in each nostril 2-3 times / day.
3. Children aged 1 to 6 years should be prescribed drops of 0.025% 1-2 drops in each nostril 2-3 times / day.
4. Adults and children over 6 years should be prescribed drops of 0.05% 1-2 drops in each nostril 2-3 times / day.

To ensure the accuracy of the dosage, the 0.01% drop bottle has a graduated pipette with the number of drops. If 1 drop is prescribed, the pipette should be filled with a solution to the mark 1.

The effectiveness of the following procedure is also proved: depending on the age of 1-2 drops 0.01% solution is applied to cotton wool and the nasal passages are wiped.

Nazivin should be used within 3-5 days. Doses in excess of those recommended are prescribed at the doctor's discretion.

Side effects

Side effects when applying Nazivin occur infrequently. Possible burning, dry nasal mucosa and sneezing. Rarely occurs reactive hyperemia - severe nasal congestion when the effect of the drug is weakened.

Overdose

Overdose of oxymetazoline occurs when a large amount of substance enters the digestive tract and the bloodstream. This can happen when a small child has access to drops and accidentally drinks them. Parents are strongly advised to keep any medication out of the reach of the child.

When topical application of drops according to the instructions, an overdose is excluded. But at the same time there is a risk when using drugs with a high concentration of the active ingredient to treat young children.

Manifestations of severe overdose:

• temperature increase to subfebrile;
• violation of breathing due to edema;
• mental and neural disorders;
• increased blood pressure;
• arrhythmia, difficulty breathing;
• narrowing of the pupils;
• drowsiness and decreased activity.

When a life-threatening amount of substance enters the blood, a sharp decrease in body temperature occurs, respiratory depression, and a reduction in the frequency of cardiac contractions. This can result in stopping breathing and developing a coma.

Treatment: taking activated charcoal and washing the baby's stomach.

special instructions

Avoid prolonged use and overdose of the drug, especially in children.

After long-term use of drugs containing oxymetazoline, in doses exceeding the recommended, it is impossible to exclude the total influence on the cardiovascular system and the central nervous system; in these cases, the ability to drive a vehicle or equipment can decrease.

Drug Interactions

With the simultaneous use of Nazivin with MAO blockers or tricyclic antidepressants, there is an increase in blood pressure.

Co-administration of other vasoconstrictive drugs increases the risk of side effects.

Reviews

We picked up some feedback from parents who used Nazivin for children:

1. Nastya. When the child had a runny nose, I immediately began to wash her nose with saline. But he allowed only to quickly remove the mucus, but to cope with nasal congestion it was possible only Nazivin. I used the drug for only 3 days and such an unpleasant symptom as the runny nose disappeared.
2. Svetlana. My babies have been treated by Nazivin for 5 years already. They are small, so they often get sick, and these drops quickly restore the breathing of the nose. They do not cause irritation of the mucous and burning, like some other drugs. The pipette is always on the vial - it's convenient, you do not have to look for it, boil it, clean it up somewhere, so that the kids will not play with it.
3. Vera. Nasivin children perfectly copes with stuffy nose in my grandson. He is 5 years old, but the trips to the garden in the cold season always end in the fact that he is sick. I tried a lot of drops: Pinosol, Otrivin, but we could not get such effect as from Nazivin. It is enough for us to swallow 3-4 days a child's nose, as the cold immediately recedes

Analogues

Each drug has analogs that have the same active ingredient:

1. Noxivin - the composition includes eucalyptus oil, used for all manifestations of the common cold, for women during pregnancy - with caution;
2. Nozakar baby - the composition includes moisturizers. For all forms of the common cold children from one to three years are not recommended, women during pregnancy - with caution;
3. Nasol is a drug with similar properties, like Nazivin. The only difference: it is produced only as a spray and for children from one to six years and women can not be applied from a cold during pregnancy;
4. Operil - comes out as a drop and spray. Apply to children of two years and above, if a cold occurs. This drug is administered to women during pregnancy according to the instructions.

Before using analogues, consult your doctor.

Storage conditions and shelf life

Keep the drug at a temperature of up to +25 degrees. Keep away from children.

Shelf life 3 years.

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