How to use Biltricide tablets in a dosage of 600 mg

Biltricide - one of the names of such a tool as prazikvantel.

These pills are effective for many types of helminths, but they need to be taken with caution. The medication acts by enhancing the permeability of helminth cell membranes for calcium ions. After the concentration of calcium rises, parasites break down carbohydrate metabolism and reduce muscle, which leads to paralysis of the worms.

On this page you will find all information about Biltricide: full instructions for use on this medication, average prices in pharmacies, complete and incomplete analogs of the drug, as well as reviews of people who have already used Biltricide. Want to leave your opinion? Please write in the comments.

Clinical and pharmacological group

Anthelmintic preparation.

Conditions of leave from pharmacies

It is released on prescription.

Price list

How much is Biltricide? The average price in pharmacies is at the level of450 rubles.

Form of issue and composition

Biltricide is available in the form of 600 mg tablets coated with a special coating. A glass bottle with a plastic stopper, contains 6 tablets. The bottle is in a cardboard box, along with the instruction.

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One tablet contains:

Praziquantel - 600 mg;
Auxiliary substances: corn starch, microcrystalline cellulose, povidone, sodium lauryl sulfate, magnesium stearate, hypromellose, macrogol 4000, titanium dioxide.

Pharmacological effect

Biltricide has a harmful effect on helminths, causing paralysis of the musculature of parasites by increasing the permeability of their membranes. In this case, the active substance of the drug stops the absorption of glucose by the cells of the worms and stimulates the release of the acidic compounds of the milk.

Together, all these actions lead to the death of helminths.

Indications for use

Biltricide tablets are prescribed for the treatment of the following diseases:

Schistomatosis of the genitourinary;
An intestinal schistosis;
Cestodoza (teniosis, diphyllobothriasis, hymenolepiasis, teniarinhoz);
Trematodoza (opisthorchiasis, metagonimosis, clonorchosis);
Paragonimosis;
Fasciolopsidosis;
Fascioliasis;
Neurocysticercosis;
Cysticercosis.

Contraindications

The drug Biltricide is not prescribed when:

against rifampicin therapy;
hypersensitivity to praziquantel and auxiliary components;
helminthiases in pediatrics in children under 4 years;
cysticercosis of the eye;
pregnancy (the first trimester is categorically contraindicated, the second and third trimester is conditionally contraindicated).

With caution Biltricide is prescribed for:

Decompensated hepatic insufficiency;
disturbances in the rhythm of the myocardium;
hepatolienne schistosomiasis.

Application in pregnancy and lactation

Biltricide is not recommended in the first trimester of pregnancy.

When carrying out a short course of Biltricide therapy, breastfeeding should be suspended for the whole of this period and the next 24 hours.

Instructions for use

The instructions for use indicate that Biltricide is prescribed for adults and children over 4 years of age.

The tablet should be taken whole inside, not liquid, with a small amount of liquid before or during meals. If you are recommended to take 1 time / day, then the pill should be taken in the evening. With repeated use of the drug during the day, it is recommended to observe the interval between doses not less than 4 hours and not more than 6 hours.

Biltricide doses are set strictly individually and depend on the type of pathogen.

In infections caused by Schistosoma mansoni and Schistosoma intercalatum: 40 mg / kg once / day or 20 mg / kg 2 times / day. Duration of treatment - 1 day.
In infections caused by Schistosoma haematobium: 40 mg / kg body weight once. Duration of treatment - 1 day.
In infections caused by Clonorchis sinensis, Opisthorchis viverrini: 25 mg / kg 3 times / day for 1-3 days.
In infections caused by Schistosoma japonicum, Schistosoma mekongi: 60 mg / kg 1 time / day or 30 mg / kg 2 times / day. Duration of treatment - 1 day.
In infections caused by Paragonimus westermani and other species: 25 mg / kg 3 times / day for 2-3 days.

Side effects

One of the main unpleasant symptoms arising after the mass death of helminths caused by Biltricide is a general intoxication of the body. The drug begins to act almost immediately, and the maximum concentration in the blood is reached after 1-2 hours after application.

Then the following symptoms occur:

Arrhythmia, high blood pressure.
Allergic skin rashes.
Increased body temperature, chills, general febrile state.
Sore joints, muscles, bones.
Gastrointestinal Disorder - nausea, vomiting, anorexia, diarrhea, possibly with an admixture of blood in the stool.
Headache and dizziness, sometimes accompanied by cramps, numbness of limbs.

As a result of treatment with Biltricide, there is also a retardation of reactions, fatigue, drowsiness.

Overdose

Data on excess doses of praziquantel with serious symptoms and consequences are absent. It is theoretically possible to intensify the manifestations of side effects of the drug when therapeutic doses are exceeded.

special instructions

On the day or days of taking the drug, as well as within 24 hours after using Biltricid, it is recommended to refrain from driving or other moving machinery.
In case of heart rhythm disturbances and simultaneous admission with medicine based on digitalis, Biltricide is taken under medical supervision.
Persons living or living in territories endemic for trematodosis and cysticercosis are recommended hospital treatment.
With hepatolienne schistosomiasis and decompensated hepatic insufficiency, the use of Biltricide requires caution. This is associated with the risk of a longer presence in the vascular bed of increased concentration of praziquantel. Patients with these diseases can be hospitalized for the period of treatment.

Drug Interactions

Indicators of the liver lower the concentration of the drug in the blood.
Inhibitors of the liver increase the concentration of the active ingredient.
The efficacy of the agent is significantly reduced when used concomitantly with dexamethasone.

Reviews

We picked up some feedback from people about the Biltricide drug:

Kostya. I advise taking pills "biltricid" 10 minutes after the end of the meal with a small but sufficient to swallow the amount of cooled boiled water and after taking 2 hours of tablets, do not drink anything and do not eat (or do not take it into your mouth). (Nausea, vomiting, diarrhea can be caused by poisoning products of decay of dead parasites).

On the forums, the opinions of the patients testify to the effectiveness of the tablets, the reviews about the treatment of opisthorchiasis with Biltricide are positive. The remedy is struggling with flukes and schistosomes, however, it has strong toxicity and side effects, such as: severe weakness, headaches, dizziness, nausea.

Analogues

Biltricide is one of the most popular and effective remedies against parasites, but it does not suit everyone. A similar effect and effectiveness is provided by the following tablets: